SS18

Synovial sarcoma translocation, chromosome 18
Estructuras disponibles
PDB	Buscar ortólogos: PDBe, RCSB
Identificadores
Símbolos	SS18 (HGNC: 11340) MGC116875; SSXT; SYT
Identificadores; externos	OMIM: 600192 ; EBI: SS18; GeneCards: Gen SS18; UniProt: SS18;
Locus	Cr. 18 q11.2
	Referencias: AmiGO / QuickGO
Ortólogos
Humano	Ratón
6760
Q15532	n/a
NP_001007560	n/a
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La proteína SSXT (SS18) subunidad SS18 del complejo de remodelación de cromatina BAF es una proteína codificada en humanos por el gen SS18.^[1]^[2]^[3]^[4]

Interacciones

La proteína SS18 ha demostrado ser capaz de interaccionar con:

Sinónimos

SYT, SSXT, SMARCL1

Referencias

↑ Shipley JM, Clark J, Crew AJ, Birdsall S, Rocques PJ, Gill S, Chelly J, Monaco AP, Abe S, Gusterson BA, et al. (mayo de 1994). «The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome». Oncogene 9 (5): 1447-53. PMID 8152806.
↑ Clark J, Rocques PJ, Crew AJ, Gill S, Shipley J, Chan AM, Gusterson BA, Cooper CS (Dec de 1994). «Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma». Nat Genet 7 (4): 502-8. PMID 7951320. doi:10.1038/ng0894-502.
↑ de Bruijn DR, Geurts van Kessel A (Feb de 2006). «Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci». Cytogenet Genome Res 112 (3-4): 222-6. PMID 16484776. doi:10.1159/000089874.
↑ «Entrez Gene: SS18 synovial sarcoma translocation, chromosome 18».
↑ de Bruijn, D R; dos Santos N R, Thijssen J, Balemans M, Debernardi S, Linder B, Young B D, Geurts van Kessel A (mayo. de 2001). «The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10». Oncogene (England) 20 (25): 3281-9. ISSN 0950-9232. PMID 11423977. doi:10.1038/sj.onc.1204419.
↑ Eid, J E; Kung A L, Scully R, Livingston D M (Sep. de 2000). «p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion». Cell (UNITED STATES) 102 (6): 839-48. ISSN 0092-8674. PMID 11030627.
↑ Kato, Hiroyuki; Tjernberg Agneta, Zhang Wenzhu, Krutchinsky Andrew N, An Woojin, Takeuchi Tamotsu, Ohtsuki Yuji, Sugano Sumio, de Bruijn Diederik R, Chait Brian T, Roeder Robert G (Feb. de 2002). «SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones». J. Biol. Chem. (United States) 277 (7): 5498-505. ISSN 0021-9258. PMID 11734557. doi:10.1074/jbc.M108702200.
↑ Perani, Michela; Ingram Catherine J E, Cooper Colin S, Garrett Michelle D, Goodwin Graham H (Nov. de 2003). «Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers». Oncogene (England) 22 (50): 8156-67. ISSN 0950-9232. PMID 14603256. doi:10.1038/sj.onc.1207031.

Enlaces externos

En HomoloGene: SS18

Literatura del gen SS18 a través de RARe-SOURCE

[pmid8152806-1] Shipley JM, Clark J, Crew AJ, Birdsall S, Rocques PJ, Gill S, Chelly J, Monaco AP, Abe S, Gusterson BA, et al. (mayo de 1994). «The t(X;18)(p11.2;q11.2) translocation found in human synovial sarcomas involves two distinct loci on the X chromosome». Oncogene 9 (5): 1447-53. PMID 8152806.

[pmid7951320-2] Clark J, Rocques PJ, Crew AJ, Gill S, Shipley J, Chan AM, Gusterson BA, Cooper CS (Dec de 1994). «Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma». Nat Genet 7 (4): 502-8. PMID 7951320. doi:10.1038/ng0894-502.

[pmid16484776-3] Bruijn DR, Geurts van Kessel A (Feb de 2006). «Common origin of the human synovial sarcoma associated SS18 and SS18L1 gene loci». Cytogenet Genome Res 112 (3-4): 222-6. PMID 16484776. doi:10.1159/000089874.

[entrez-4] «Entrez Gene: SS18 synovial sarcoma translocation, chromosome 18».

[pmid11423977-5] Bruijn, D R; dos Santos N R, Thijssen J, Balemans M, Debernardi S, Linder B, Young B D, Geurts van Kessel A (mayo. de 2001). «The synovial sarcoma associated protein SYT interacts with the acute leukemia associated protein AF10». Oncogene (England) 20 (25): 3281-9. ISSN 0950-9232. PMID 11423977. doi:10.1038/sj.onc.1204419.

[pmid11030627-6] Eid, J E; Kung A L, Scully R, Livingston D M (Sep. de 2000). «p300 interacts with the nuclear proto-oncoprotein SYT as part of the active control of cell adhesion». Cell (UNITED STATES) 102 (6): 839-48. ISSN 0092-8674. PMID 11030627.

[pmid11734557-7] Kato, Hiroyuki; Tjernberg Agneta, Zhang Wenzhu, Krutchinsky Andrew N, An Woojin, Takeuchi Tamotsu, Ohtsuki Yuji, Sugano Sumio, de Bruijn Diederik R, Chait Brian T, Roeder Robert G (Feb. de 2002). «SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones». J. Biol. Chem. (United States) 277 (7): 5498-505. ISSN 0021-9258. PMID 11734557. doi:10.1074/jbc.M108702200.

[pmid14603256-8] Perani, Michela; Ingram Catherine J E, Cooper Colin S, Garrett Michelle D, Goodwin Graham H (Nov. de 2003). «Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers». Oncogene (England) 22 (50): 8156-67. ISSN 0950-9232. PMID 14603256. doi:10.1038/sj.onc.1207031.

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